Oscar Quintanilla ’28 Asks, ‘Why Don’t Frogs Get Fevers?’ tmfonda@colgate.edu Fri, 08/15/2025 - 11:25 Since his first semester at Colgate, Oscar Quintanilla ’28 has worked alongside Assistant Professor of Psychological and Brain Sciences Anzela Niraula to research the neural and immune mechanisms of tadpoles. Sponsored by Colgate’s Science and Technology Accelerated Research Scholars (STARS) program, his project now continues into the summer, as Quintanilla and fellow researcher Ella Duchnowska ’26 investigate a shared research question: Why don’t frogs get fevers? Founded in 2022 by Professor of Biology Krista Ingram, the STARS program supports first-generation college students and students from high schools offering limited science preparation by pairing them with faculty mentors early in their time at Colgate. During the academic year, they receive 4–6 hours of weekly work-study experience that may carry into the summer. A neuroscience major on the pre-med track, Quintanilla is also active in the Minority Association of Pre-Med Students (MAPS) and the neuroscience club. Accordingly, his research project “exists at the intersection of immunology and neuroscience.” Under Professor Niraula’s mentorship, he’s testing how differences in thermoregulation, or the ability to control body temperature, shape immune responses in frogs compared to humans.   “Warm-blooded species maintain a constant internal temperature using energy from food,” says Quintanilla. “But cold-blooded species, like frogs, rely on external sources like the sun. That actually affects how they handle infections.” In humans, a fever is one of the body’s foremost immune defenses — an internal temperature spike that helps eliminate bacteria. “Bacteria like our normal body temperature, but if it gets hotter inside, they can’t do their work,” says Quintanilla. Frogs, however, can’t generate heat on their own. Instead, they seek it out. “They’ll move to warmer environments to help fight off infection,” he explains: a behavior the group expects to observe in the lab. There, infected frogs naturally gravitate toward warmer water. Using a population of over 90 tadpoles, the team is also studying whether microglia, the brain’s waste-clearing immune cells, play a role in the metamorphic changes that take place as tadpoles become frogs. Through immunohistochemistry, a technique that uses antibodies to visualize proteins in tissue samples, Quintanilla has begun analyzing frog brain matter to probe that question further. “Collecting and analyzing slices is so rewarding,” he says, sharing his aspiration to pursue a future career as a neurosurgeon. “It helps me build on my surgical skills, and in the long term, it’ll be a form of experience.”   Natural Sciences and Mathematics Research News and Updates Student Psychological and Brain Sciences

Ekra Hoque ’26 Investigates Food Safety in Bangladesh tmfonda@colgate.edu Thu, 08/14/2025 - 14:19 This summer, Ekra Hoque ’26 has taken her biochemistry training home to Bangladesh, where she’s investigating a critical public health issue: food safety. At BRAC University in Dhaka, she’s exploring what it’s like to conduct scientific research in the place where she hopes to build her future career. Hoque’s experience is supported by Career Services’ Summer Internship Funding program, which is designed to help offset related expenses. Her host institution, BRAC University, was established in 2001 by Sir Fazle Hasan Abed, the founder of BRAC, one of the world’s largest nongovernmental organizations. Modeled on the American liberal arts college system, the university shapes future leaders who can balance academic excellence with empathetic leadership. At BRAC, Hoque joined a large microbiology lab to investigate the quality and safety of food commonly sold in open-air markets — “where affordability often comes at the cost of hygiene,” Hoque says. “Many people in Bangladesh, especially those living in poverty, rely on these markets for daily food, but they’re not always safe.” Her research involved collecting items such as fruits, dates, grains, and nuts, and testing them for microbial and fungal contamination. “When I started off, I was looking for aflatoxins,” Hoque says. These are spores produced by fungal growth on food that can have toxic effects. But as her testing commenced, she found these and more: gram-positive and gram-negative bacteria, lactose fermenters and non-fermenters. “While some of these microbes occur naturally in the human body, they may pose health risks when consumed in large quantities through contaminated food,” says Hoque. “I think that, with further research, we’ll be able to better understand how these microbes affect consumers.” Along the way, Hoque has learned several new lab techniques, including culturing cells, PCR (polymerase chain reaction), and ELISA, a test used to detect specific bacteria and fungi. “Working in a large, high-volume lab environment was such an educational experience for me,” she adds. “I had to keep up with the pace and, many times, work independently. My long-term goals include coming back to Bangladesh and working as a professor here, conducting research.” Short term, Hoque and her BRAC colleagues hope to build on this work by collecting hospital data and exploring the broader correlations between food contamination and public health in Bangladesh. “Through this work, we hope to raise awareness and explore safer, more sustainable alternatives,” says Hoque. Visit Career Services online for more information about summer internship funding at Colgate. Academics Research Career Development News and Updates Student Department of Chemistry Ekra Hoque ’26

In honor of Colgate’s Bicentennial year, the Picker Art Gallery is hosting a special traveling exhibition, Koolanga Boodja Neh Nidjuuk (Children Looking and Listening on Country), through June 30. The post Repatriation and Reconciliation: The Carrolup Artworks Return to Colgate first appeared on Colgate University News.

Grafters X Change: Branches and Networks brought together Colgate and local community members, eco-artists, and activists to foster creative community resiliency. The post Grafters X Change Builds Community Resiliency first appeared on Colgate University News.